PT  - JOURNAL ARTICLE
AU  - Kozhevnikova, Olga
AU  - Namazova-Baranova, Leyla
AU  - Abashidze, Eka
AU  - Lebedev, Vlad
AU  - Antonova, Elena
AU  - Logacheva, Olga
AU  - Batyrova, Anna
AU  - Shirokova., Irina
TI  - P153 Height≥85 percentile with increased body mass index (BMI) is risk factor for cardio-vascular diseases height≥85 percentile with increased body mass index (BMI) is risk factor for cardio-vascular diseases
AID  - 10.1136/archdischild-2017-313273.241
DP  - 2017 Jun 01
TA  - Archives of Disease in Childhood
PG  - A93--A93
VI  - 102
IP  - Suppl 2
4099  - http://adc.bmj.com/content/102/Suppl_2/A93.1.short
4100  - http://adc.bmj.com/content/102/Suppl_2/A93.1.full
SO  - Arch Dis Child2017 Jun 01; 102
AB  - Background It was marked that children with increased BMI have high height due to insulin resistance or elevating insulin/IGF1. The Insulin resistant can be reason of cardio-vascular diseases.Aim to find the early detection of risk factors for cardiovascular diseases in children with height≥85 percentile age-sex normMethods 854 children aged 3–17 y.o. were examined (included 87 with height≥85 percentile): by arterial stiffness device (TensioMed,Hungary) – 211; by 24 hour monitoring of ECG and blood pressure(Astrocard, Russia) – 92; by Polysomnography (Embla-S7000,USA)- 45; by system of continuous glucose monitoring (Guardian, USA) – 14 children.Results Children with increased BMI and with height≥85 percentile in comparison with middle height had a significantly lower augmentation index, in 5 times more often – decreased diastolic blood pressure at night, lower level of high density lipoproteids; if they had obesity- the normal 24 hour dynamics of blood pressure was disappeared, if they had overweight- there was more longer QT interval at night, if they had sleep obstructive apnea-hypopnea syndrom there were some periods of glycemia less then 3.3 mmol/L at night.Conclusions Children with height≥85 percentile of age- and gender-based norms with increased BMI and, especially, with nasal obstruction have an additional risk of cardio-vascular diseases.Disclosure of Interest None Declared