High flow oxygen therapy (HFOT) appears to associated with a significantly longer length-of-stay and an increased admission rate to intensive care units compared with standard oxygen therapy in children (aged 1 year to 4 years) requiring oxygen therapy support for their respiratory failure. Maria de Benedictus F warned us of the most important learning from the Odyssey; that is returning safely to Ithaca by resisting the sweet song of the Sirens (JAMA Pediatr 2019;173:125–126. doi:10.1001/jamapediatrics.2018.3831) after publication of the PARIS one study examining the role of HFOT in bronchiolitis (Franklin D et al. N Engl J Med 2018;378:1121–1131. doi:10.1056/NEJMoa1714855 …