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Miscellanea
Images in paediatrics
Progressive multifocal leukoencephalopathy in children with HIV: still a challenge
  1. Beatriz Sousa Nunes1,
  2. Cláudia Marques-Matos2,
  3. Carla Conceição3,
  4. Tiago Milheiro Silva1
  1. 1 Infectious Diseases Unit, Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal
  2. 2 Pediatric Neurology Unit, Hospital de Dona Estefânia, Centro Hospitalar Universitário Lisboa Central, Lisboa, Portugal
  3. 3 Imagiology Department, Neuroradiology, Hospital de Dona Estefânia, Centro Hospitalar Universitário Lisboa Central, Lisboa, Portugal
  1. Correspondence to Dr Beatriz Sousa Nunes, Infectious Diseases Unit, Hospital de Dona Estefânia, Centro Hospitalar Universitário Lisboa Central. Rua Jacinta Marto, 1169-045, Lisboa, Portugal; mbeatrizsnunes{at}gmail.com

https://doi.org/10.1136/archdischild-2023-326609

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    A male teenager from Guinea-Bissau, in Portugal for 15 days, presented with a two-month history of progressive headache, decreased vision and left hemiparesis. On neurological examination, the left eye was inwardly and downwardly deviated, with limited abduction and elevation, and predominantly distal left hemiparesis was noted. His gait was mildly ataxic with spastic circumduction of his left leg. Brain MRI (figure 1) showed multiple areas of fluid-attenuated inversion recovery (FLAIR) …

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    Footnotes

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.